By David J. Matthews,Mary E. Gerritsen
ISBN-10: 0470229659
ISBN-13: 9780470229651
Research has proven that protein kinases can instigate the formation and unfold of melanoma once they transmit defective indications within cells. due to this truth, pharmaceutical scientists have distinct kinases for in depth learn, and feature been operating to improve medicinal roadblocks to sever their malignant technique of communication.
Complete with full-color displays, Targeting Protein Kinases for melanoma Therapy defines the structural positive factors of protein kinases and examines their mobile capabilities. Combining kinase biology with chemistry and pharmacology purposes, this publication enlists rising facts to force the invention of latest cancer-fighting medicinal drugs. invaluable info includes:
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Comprehensive overviews of the main kinase households taken with oncology, integrating protein constitution and serve as, and delivering very important instruments to help pharmaceutical researchers to appreciate and paintings during this dynamic zone of melanoma drug research
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Focus on small molecule inhibitors in addition to different healing modalities
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Discussion of kinase inhibitors that experience entered scientific trials for the remedy of melanoma, with an emphasis on molecules that experience advanced to overdue degree scientific trials and, in a couple of situations, to market
Providing a platform for extra learn, this significant paintings stories either the successes and demanding situations of kinase inhibitor treatment, and offers perception into destiny instructions within the struggle opposed to cancer.
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Extra info for Targeting Protein Kinases for Cancer Therapy
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Targeting Protein Kinases for Cancer Therapy by David J. Matthews,Mary E. Gerritsen
by George
4.1