Pharmacology

Read e-book online Good Cascade Impactor Practices, AIM and EDA for Orally PDF

By Terrence P. Tougas,Jolyon P. Mitchell,Svetlana A. Lyapustina

ISBN-10: 1461462959

ISBN-13: 9781461462958

ISBN-10: 1489979468

ISBN-13: 9781489979469

the aim of this ebook is to introduce a brand new, easier and more suitable method during which to interpret pharmaceutical aerosol particle dimension facts from orally inhaled items (OIPs). at present, the compendial and regulatory standards dictate the necessity for measurements by means of complete answer multi-stage cascade impactor (CI), a method that's difficult for the operator, time eating, at risk of experimental errors, and not easy for procedure transfers from one laboratory to a different. in addition, we will exhibit that the present perform of lowering details from mass-weighted aerodynamic particle measurement distribution (APSD) measurements by utilizing CI degree groupings isn't the ideal decision-making device for OIP quality controls (QC) compared to newly brought, mutually-independent effective info research (EDA) metrics that may be derived both from complete answer or abbreviated impactor measurements (AIM).

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Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products by Terrence P. Tougas,Jolyon P. Mitchell,Svetlana A. Lyapustina


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