Basic Medical Science

Roger L. Lundblad's Biotechnology of Plasma Proteins (Protein Science) PDF

By Roger L. Lundblad

ISBN-10: 1439850267

ISBN-13: 9781439850268

The fractionation of human blood plasma should be thought of to be a mature undefined, with the fundamental know-how, alcohol fractionation, courting again at the very least to the Nineteen Forties. some of the items defined within the present paintings were authorized biologics because the Fifties. the data accumulated from the advance of plasma proteins has proved very important to the improvement of recombinant healing proteins.

Discussing the function of plasma proteins in present biotechnology, Biotechnology of Plasma Proteins describes the protein composition of human plasma, the fractionation of plasma to acquire healing proteins, and the research of those items. It delineates the trail from plasma items to recombinant items, and highlights items from albumin, intravenous immunoglobins, and coagulation. It deals a complete evaluation of present strategies for the research of proteins together with electrophoresis, chromatography, spectrophotometry, mass spectrometry, and updates now not released on account that 1975.

Key Topics

Protein Composition of Plasma

  • Proteomic tools for plasma protein analysis

  • Plasma protein biomarkers

  • Validation of biomarkers

  • Assays for plasma biomarkers

Methods for the research of Protein Products

  • Assay improvement and validation

  • Electrophoresis

  • Chromatography

  • Immunoassay

  • Mass spectrometry

  • Raman spectroscopy

Plasma Fractionation: historic and glossy Methods

  • Development of Cohn alcohol fractionation

  • Industrial methods

  • Development of chromatographic methods

Plasma Protein items of healing Value

  • Albumin

  • Intravenous immunoglobulin

  • Coagulation products

  • Growth factors

  • Wound management

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Biotechnology of Plasma Proteins (Protein Science) by Roger L. Lundblad

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